Alginate Compositions and Uses Thereof

Smadar Cohen (Inventor), Yaron Ilan (Inventor), Eyal Shteyer (Inventor), Ami Ben-Ya'acov (Inventor)

Research output: Patent


Compositions comprising an alginate, a source of sodium ions and a carrier (e.g., a pharmaceutically acceptable carrier), which are characterized by reduced association of the alginate chains and hence by at least one of: (i) a zeta potential weaker than −25 mV, at a concentration of 0.5% (w/v) alginate in the carrier; and (ii) a diffusion coefficient of at least 10−8 cm2/second, at a concentration of 0.5% (w/v) alginate in the carrier, are disclosed. Also disclosed are uses of the composition and methods utilizing the composition for treating inflammatory bowel disease; liver damage, diseases and disorders, for treating a medical condition treatable by a hepatotoxic agent and for reducing or preventing liver damage, including liver damage caused by a hepatotoxic agent.
Original languageEnglish GB
Patent numberUS10500226B2
StatePublished - 10 Dec 2019


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