Alternating hemiplegia of childhood in half-sisters

Uri Kramer, Yoram Nevo, Dov Margalit, Zamir Shorer, Shaul Harel

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


We present the family of two girls affected with alternating hemiplegia of childhood who were born to the same mother and different fathers. Previous reports suggested mitochondrial dysfunction as an etiologic mechanism for this disorder. Muscle biopsy including a measurement of the respiratory chain enzymes, performed in one of the sisters showed no mitochondrial abnormalities. The mode of inheritance is not certain, but an autosomal- dominant gene is most likely.

Original languageEnglish
Pages (from-to)128-130
Number of pages3
JournalJournal of Child Neurology
Issue number2
StatePublished - 1 Jan 2000
Externally publishedYes

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology


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