An association between fibromyalgia and the dopamine D4 receptor exon III repeat polymorphism and relationship to novelty seeking personality traits

D. Buskila, H. Cohen, L. Neuman, R. P. Ebstein

    Research output: Contribution to journalArticlepeer-review

    134 Scopus citations

    Abstract

    Fibromyalgia (FMS) is a common syndrome consisting of diffuse aching, pain, or stiffness in the muscles or joints, accompanied by multiple tender points on examination. FMS patients are characterized by an atypical personality profile, high on harm avoidance and low on novelty seeking. The current study showed a decreased frequency in FMS of a dopamine D4 receptor polymorphism, the 7 repeat, associated in some studies with novelty seeking.

    Original languageEnglish
    Pages (from-to)730-731+727
    JournalMolecular Psychiatry
    Volume9
    Issue number8
    DOIs
    StatePublished - 1 Aug 2004

    ASJC Scopus subject areas

    • Molecular Biology
    • Psychiatry and Mental health
    • Cellular and Molecular Neuroscience

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