Abstract
A continuous three‐step micro‐synthesis of 1,2‐dibromo‐3‐chloropropane, labelled with tritium in position 1 and 2, is described. A specific activity of 10.8 Ci/mmol is obtained. The yield observed in the uninterrupted overall synthesis is appreciably lower than that in the controlled step‐by‐step synthesis.
| Original language | English |
|---|---|
| Pages (from-to) | 1713-1719 |
| Number of pages | 7 |
| Journal | Journal of Labelled Compounds and Radiopharmaceuticals |
| Volume | 18 |
| Issue number | 12 |
| DOIs | |
| State | Published - 1 Jan 1981 |
| Externally published | Yes |
Keywords
- Dibromochloropropane
- tritium labelling
ASJC Scopus subject areas
- Analytical Chemistry
- Biochemistry
- Radiology Nuclear Medicine and imaging
- Drug Discovery
- Spectroscopy
- Organic Chemistry