Abstract
The BioPhorum Development Group is an industry collaboration enabling the sharing of common practices for the development of biopharmaceuticals. Bioassays are an important part of an analytical control system. Utilization of ready-to-use cells can increase operational flexibility and improve efficiency by providing frozen cell banks uniform stock while removing challenges associated with maintaining cultured cells. The BioPhorum Development Group-Bioassay workstream conducted an intercompany benchmarking survey and group discussions around the use of ready-to-use cells for bioassays. The results of the collaboration provide alignment on nomenclature, production, qualification and implementation of ready-to-use cells to support the assay life cycle.
Original language | English |
---|---|
Pages (from-to) | 135-144 |
Number of pages | 10 |
Journal | BioTechniques |
Volume | 76 |
Issue number | 4 |
DOIs | |
State | Published - 1 Jan 2024 |
Keywords
- bioassay
- biologicals
- cell-based assay
- development
- ready-to-use cells
ASJC Scopus subject areas
- Biotechnology
- General Biochemistry, Genetics and Molecular Biology