An open pilot study of interpersonal psychotherapy for panic disorder (IPT-PD)

Joshua D. Lipsitz, Merav Gur, Nina L. Miller, Nicholas Forand, Donna Vermes, Abby J. Fyer

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


Interpersonal psychotherapy (IPT) is a time-limited psychotherapy initially developed to treat depression. It has yet to be studied systematically for treatment of panic disorder. We modified IPT for the treatment of panic disorder and tested this treatment in an open clinical trial with 12 patients seeking treatment of DSM-IV panic disorder. Patients were assessed before during and after treatment. At completion of treatment, nine patients (75%) were independently categorized as responders (i.e., rated as much improved or very much improved on the Clinical Global Impression-Change Scale). Substantial improvement was found for panic symptoms, associated anxiety and depressive symptoms, and physical and emotional well-being. Degree of change in this sample approximated that obtained in studies using established treatments such as cognitive behavioral therapy. Results, though preliminary, suggest that IPT may have efficacy as a primary treatment of panic disorder. Further study is warranted.

Original languageEnglish
Pages (from-to)440-445
Number of pages6
JournalJournal of Nervous and Mental Disease
Issue number6
StatePublished - 1 Jun 2006
Externally publishedYes


  • Anxiety
  • IPT
  • Interpersonal
  • Panic
  • Psychotherapy

ASJC Scopus subject areas

  • Psychiatry and Mental health


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