An outbreak of Streptococcus pneumoniae serotype 1 in a closed community in southern Israel

Ron Dagan; Serge Gradstein; Ilana Belmaker; Nurith Porat; Yaffa Siton; Gabriel Weber; Jacob Janco; Pablo Yagupsky

doi:10.1086/313645

An outbreak of Streptococcus pneumoniae serotype 1 in a closed community in southern Israel

Ron Dagan, Serge Gradstein, Ilana Belmaker, Nurith Porat, Yaffa Siton, Gabriel Weber, Jacob Janco, Pablo Yagupsky

Research output: Contribution to journal › Article › peer-review

80 Scopus citations

Abstract

An outbreak of Streptococcus pneumoniae serotype 1 occurred in a closed community that was characterized by poverty and crowding. Vaccine was administered to individuals aged >2 years; no new cases occurred among vaccine recipients. Six weeks after vaccination, carriage of serotype 1, but not of other serotypes, decreased 8.8-fold. This suggests that the reduction in serotype 1 carriage reflects the natural course of the outbreak rather than a vaccine effect. Polysaccharide vaccine may be helpful in terminating pneumococcal outbreaks but may not affect pneumococcal carriage.

Original language	English
Pages (from-to)	319-321
Number of pages	3
Journal	Clinical Infectious Diseases
Volume	30
Issue number	2
DOIs	https://doi.org/10.1086/313645
State	Published - 15 Mar 2000

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1086/313645

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AU - Siton, Yaffa

AU - Weber, Gabriel

AU - Janco, Jacob

AU - Yagupsky, Pablo

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AB - An outbreak of Streptococcus pneumoniae serotype 1 occurred in a closed community that was characterized by poverty and crowding. Vaccine was administered to individuals aged >2 years; no new cases occurred among vaccine recipients. Six weeks after vaccination, carriage of serotype 1, but not of other serotypes, decreased 8.8-fold. This suggests that the reduction in serotype 1 carriage reflects the natural course of the outbreak rather than a vaccine effect. Polysaccharide vaccine may be helpful in terminating pneumococcal outbreaks but may not affect pneumococcal carriage.

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An outbreak of Streptococcus pneumoniae serotype 1 in a closed community in southern Israel

Abstract

ASJC Scopus subject areas

UN SDGs

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