Anticancer natural product from marine invertebrates

Rajesh Kumar Singh, Amit Ranjan, Monika Singh, Akhileshwar Kumar Srivastava

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

3 Scopus citations

Abstract

Marine invertebrates have been used as therapeutics as well as food since a long time, because of varieties of bioactive compounds and nutrients. The invertebrate marine animals which belong to phylum Porifera, Cnidaria, Annelida, Arthropoda, Mollusca, and Echinodermata represent the animals with the richest biodiversity. These invertebrates have been identified as the main source for marine-derived drug discovery, attributing about 65% of the marine natural products reported to date. The cnidarians have described in many traditional medicine system for medicine for therapeutic use. Most of anticancer marine natural compounds have been isolated from cnidarians, especially from corals. The extensive research on marine natural compounds isolated from invertebrates has showed an opportunity for development of several potent anticancer drugs, as these molecules have been reported for their various modes of action, targeting cell receptors to genetic materials of cancer cells. The anticancer natural product isolated from marine invertebrate have described in this chapter with their mode of action and molecular targets.

Original languageEnglish
Title of host publicationEvolutionary Diversity as a Source for Anticancer Molecules
PublisherElsevier Science Ltd.
Pages255-266
Number of pages12
ISBN (Electronic)9780128217108
ISBN (Print)9780128216989
DOIs
StatePublished - 1 Jan 2020
Externally publishedYes

Keywords

  • Anticancer
  • Invertebrates
  • Marine
  • Natural compounds
  • Sea-food
  • Sponges

ASJC Scopus subject areas

  • General Agricultural and Biological Sciences
  • General Biochemistry, Genetics and Molecular Biology

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