Antihyperglycemic effect of Makaradhwaja on streptozotacin induced diabetes in rats

S. Khedekar, B. J. Patgiri, B. Ravishankar, P. K. Prajapati

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


The antihyperglycemic effect of Makaradhwja was assessed in normal rats by injecting streptozotacin at 45 mg/kg to induce hyperglycemia. Powdered form of Makaradhwaja(Red sulphide of mercury) and Guduchi Ghana(dried extract of Tinospora cordifolia) with Honey was administered orally at 22.5 mg/ kg dose levels for 15 days. Serum glucose, serum cholesterol, serum triglyceride, blood urea, serum creatinine, serum alkaline phosphatase, serum bilirubin were estimated using standard methods. It was found effective antihyperglycemic (193.25±86.73) compared with reference standard (430.60±93.96).

Original languageEnglish
Pages (from-to)16-24
Number of pages9
JournalJournal of Global Pharma Technology
Issue number3
StatePublished - 1 Mar 2012
Externally publishedYes


  • Guduchi Ghana (Dried extract of Tinospora cordifolia Linn.)
  • Hyperglycemia
  • Makaradhwaja (Red Sulphide of Mercury)

ASJC Scopus subject areas

  • Pharmaceutical Science


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