TY - JOUR
T1 - Aplastic anemia in Israel
T2 - evaluation of the etiological role of chloramphenicol on a community wide basis
AU - Modan, B.
AU - Segal, S.
AU - Shani, M.
AU - Sheba, C.
PY - 1975/1/1
Y1 - 1975/1/1
N2 - A nationwide study of aplastic anemia in Israel revealed a mean yearly incidence of 7.1/1,000,000 in males and 8.7/1,000,000 in females. Twenty five per cent of the cases reported had an apparent chloramphenicol etiology. Ten patients, five treated with chloramphenicol and five without it, developed acute leukemia. The median survival was 11 months in males and 28 in females. Survival was particularly inferior in chloramphenicol related cases, suggesting that this group constitutes a specific entity.
AB - A nationwide study of aplastic anemia in Israel revealed a mean yearly incidence of 7.1/1,000,000 in males and 8.7/1,000,000 in females. Twenty five per cent of the cases reported had an apparent chloramphenicol etiology. Ten patients, five treated with chloramphenicol and five without it, developed acute leukemia. The median survival was 11 months in males and 28 in females. Survival was particularly inferior in chloramphenicol related cases, suggesting that this group constitutes a specific entity.
UR - http://www.scopus.com/inward/record.url?scp=0016588832&partnerID=8YFLogxK
U2 - 10.1097/00000441-197511000-00004
DO - 10.1097/00000441-197511000-00004
M3 - Article
AN - SCOPUS:0016588832
SN - 0002-9629
VL - 270
SP - 441
EP - 445
JO - American Journal of the Medical Sciences
JF - American Journal of the Medical Sciences
IS - 3
ER -
