Aplastic anemia in Israel: evaluation of the etiological role of chloramphenicol on a community wide basis

B. Modan, S. Segal, M. Shani, C. Sheba

Research output: Contribution to journalArticlepeer-review

28 Scopus citations

Abstract

A nationwide study of aplastic anemia in Israel revealed a mean yearly incidence of 7.1/1,000,000 in males and 8.7/1,000,000 in females. Twenty five per cent of the cases reported had an apparent chloramphenicol etiology. Ten patients, five treated with chloramphenicol and five without it, developed acute leukemia. The median survival was 11 months in males and 28 in females. Survival was particularly inferior in chloramphenicol related cases, suggesting that this group constitutes a specific entity.

Original languageEnglish
Pages (from-to)441-445
Number of pages5
JournalAmerican Journal of the Medical Sciences
Volume270
Issue number3
DOIs
StatePublished - 1 Jan 1975
Externally publishedYes

ASJC Scopus subject areas

  • Medicine (all)

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