Abstract
Three patients developed acute Guillain-Barré syndrome while on steroid treatment. The first patient suffered from ulcerative colitis and developed Guillain-Barré syndrome when the steroid dosage was being tapered. Another patient with long-standing multiple sclerosis received steroids during relapse and the Guillain-Barré syndrome appeared while treatment was reduced. The third patient, with aqueductal stenosis and ventriculoatrial shunt, who received steroids when malfunction of the shunt was suspected, developed Guillain-Barré syndrome while steroids were being tapered. Based on the putative immune pathogenesis of inflammatory demyelinating polyneuropathy, the occurrence of the syndrome in these patients could have been due to a selective effect of low-dose steroids on a specific, maybe suppressor lymphocyte subpopulation.
Original language | English |
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Pages (from-to) | 221-223 |
Number of pages | 3 |
Journal | Journal of Neurology |
Volume | 233 |
Issue number | 4 |
DOIs | |
State | Published - 1 Aug 1986 |
Externally published | Yes |
Keywords
- Corticosteroid
- Guillain-Barré syndrome
ASJC Scopus subject areas
- Neurology
- Clinical Neurology