Applications of lignin nanoparticles for cancer drug delivery: An update

Jivesh Garg, Mei Nee Chiu, Saravanan Krishnan, Lokesh Kumar Tripathi, Soumya Pandit, Bahareh Farasati Far, Niraj Kumar Jha, Kavindra Kumar Kesari, Vikas Tripathi, Sadanand Pandey, Piyush Kumar Gupta

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Cancer is one of the fast-growing diseases with an increasing trend in mortality rate worldwide. Among the treatment modalities, chemotherapy is regarded as an active therapeutic approach where anti-cancer drugs are used to kill cancer cells or arrest its growth. With the emergence of nanotechnology, nanomedicines are being developed to improve the overall pharmaceutical properties of anti-cancer drugs namely drug stability, solubility and bioavailability. Lignin-based nanomaterials are prepared from naturally available lignin polymers, a constituent of lignocellulosic biomass, showcases non-toxic behavior, biodegradable nature, and excellent absorption capacity and are well suited for biomedical applications. This review presents the recent advances on the emerging applications of lignin-based nanomaterials for cancer therapeutics. More importantly, the functional properties of lignin -nanoparticulate systems in cancer drug delivery was discussed.

Original languageEnglish
Article number131573
JournalMaterials Letters
Volume311
DOIs
StatePublished - 15 Mar 2022
Externally publishedYes

Keywords

  • Anticancer drug
  • Drug delivery
  • Lignin
  • Nanoparticles

ASJC Scopus subject areas

  • Materials Science (all)
  • Condensed Matter Physics
  • Mechanics of Materials
  • Mechanical Engineering

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