Abstract
Cancer is one of the fast-growing diseases with an increasing trend in mortality rate worldwide. Among the treatment modalities, chemotherapy is regarded as an active therapeutic approach where anti-cancer drugs are used to kill cancer cells or arrest its growth. With the emergence of nanotechnology, nanomedicines are being developed to improve the overall pharmaceutical properties of anti-cancer drugs namely drug stability, solubility and bioavailability. Lignin-based nanomaterials are prepared from naturally available lignin polymers, a constituent of lignocellulosic biomass, showcases non-toxic behavior, biodegradable nature, and excellent absorption capacity and are well suited for biomedical applications. This review presents the recent advances on the emerging applications of lignin-based nanomaterials for cancer therapeutics. More importantly, the functional properties of lignin -nanoparticulate systems in cancer drug delivery was discussed.
Original language | English |
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Article number | 131573 |
Journal | Materials Letters |
Volume | 311 |
DOIs | |
State | Published - 15 Mar 2022 |
Externally published | Yes |
Keywords
- Anticancer drug
- Drug delivery
- Lignin
- Nanoparticles
ASJC Scopus subject areas
- General Materials Science
- Condensed Matter Physics
- Mechanics of Materials
- Mechanical Engineering