TY - JOUR
T1 - Arabidopsis COP9 is a component of a novel signaling complex mediating light control of development
AU - Wei, Ning
AU - Chamovitz, Daniel A.
AU - Deng, Xing Wang
N1 - Funding Information:
Correspondence should be addressed to X.-W. D. We thank Albrecht G. von Arnim, Timothy W. McNellis, and Pilar Puente for their comments on the manuscripts and Dr. W. Gruissem (University of California, Berkeley) for providing the spinach cDNA library. This research was supported by a National Science Foundation grant (MCB-9303029) to X.-W. D. D. A. C. was a recipient of a European Molecular Biology Organization long-term fellowship.
PY - 1994/7/15
Y1 - 1994/7/15
N2 - Environmental light signals are sensed by multiple families of photoreceptors and transduced by largely unknown mechanisms to regulate plant development. In this report, genetic analysis suggested that light signals perceived by both phytochromes and a blue light receptor converge to repress the action of Arabidopsis COP9 in suppressing seedling photomorphogenesis. Molecular cloning of the gene revealed that COP9 encodes a novel protein of 197 amino acids whose expression is not regulated by light. COP9 functions as a large (>560 kDa) complex(es) that is probably subjected to light modulation. In addition, COP8 and COP11 are required for either the COP9 complex formation or its stability. Therefore COP9, together with COP8 and COP11, defines a novel signaling step in mediating light control of plant development.
AB - Environmental light signals are sensed by multiple families of photoreceptors and transduced by largely unknown mechanisms to regulate plant development. In this report, genetic analysis suggested that light signals perceived by both phytochromes and a blue light receptor converge to repress the action of Arabidopsis COP9 in suppressing seedling photomorphogenesis. Molecular cloning of the gene revealed that COP9 encodes a novel protein of 197 amino acids whose expression is not regulated by light. COP9 functions as a large (>560 kDa) complex(es) that is probably subjected to light modulation. In addition, COP8 and COP11 are required for either the COP9 complex formation or its stability. Therefore COP9, together with COP8 and COP11, defines a novel signaling step in mediating light control of plant development.
UR - http://www.scopus.com/inward/record.url?scp=0028365625&partnerID=8YFLogxK
U2 - 10.1016/0092-8674(94)90578-9
DO - 10.1016/0092-8674(94)90578-9
M3 - Article
AN - SCOPUS:0028365625
SN - 0092-8674
VL - 78
SP - 117
EP - 124
JO - Cell
JF - Cell
IS - 1
ER -