Aromatic ring cleavage of 2-amino-4-tert-butylphenol by a nonheme iron(II) complex: Functional model of 2-aminophenol dioxygenases

Biswarup Chakraborty, Tapan Kanti Paine

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

Biomimetic aromatic ring cleavage: An iron(II)-2-aminophenolate complex (see picture, right) with a tetradentate ligand reacts with dioxygen to cleave the aromatic C-C bond of 2-amino-4-tert-butylphenolate to form 4-tert-butyl-2-picolinate. This complex represents a functional model of 2-aminophenol-1,6-dioxygenase (APD) and 3-hydroxyanthranilate-3,4-dioxygenase (HAD).

Original languageEnglish
Pages (from-to)920-924
Number of pages5
JournalAngewandte Chemie - International Edition
Volume52
Issue number3
DOIs
StatePublished - 14 Jan 2013
Externally publishedYes

Keywords

  • biomimetic model
  • cleavage reactions
  • dioxygenases
  • enzyme models
  • iron

ASJC Scopus subject areas

  • Catalysis
  • General Chemistry

Fingerprint

Dive into the research topics of 'Aromatic ring cleavage of 2-amino-4-tert-butylphenol by a nonheme iron(II) complex: Functional model of 2-aminophenol dioxygenases'. Together they form a unique fingerprint.

Cite this