Aromatic ring cleavage of 2-amino-4-tert-butylphenol by a nonheme iron(II) complex: Functional model of 2-aminophenol dioxygenases

Biswarup Chakraborty; Tapan Kanti Paine

doi:10.1002/anie.201206922

Aromatic ring cleavage of 2-amino-4-tert-butylphenol by a nonheme iron(II) complex: Functional model of 2-aminophenol dioxygenases

Biswarup Chakraborty, Tapan Kanti Paine

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

Biomimetic aromatic ring cleavage: An iron(II)-2-aminophenolate complex (see picture, right) with a tetradentate ligand reacts with dioxygen to cleave the aromatic C-C bond of 2-amino-4-tert-butylphenolate to form 4-tert-butyl-2-picolinate. This complex represents a functional model of 2-aminophenol-1,6-dioxygenase (APD) and 3-hydroxyanthranilate-3,4-dioxygenase (HAD).

Original language	English
Pages (from-to)	920-924
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	52
Issue number	3
DOIs	https://doi.org/10.1002/anie.201206922
State	Published - 14 Jan 2013
Externally published	Yes

Keywords

biomimetic model
cleavage reactions
dioxygenases
enzyme models
iron

ASJC Scopus subject areas

Catalysis
General Chemistry

Access to Document

10.1002/anie.201206922

Cite this

@article{9bb762c004214c72964ee987dc76fa57,

title = "Aromatic ring cleavage of 2-amino-4-tert-butylphenol by a nonheme iron(II) complex: Functional model of 2-aminophenol dioxygenases",

abstract = "Biomimetic aromatic ring cleavage: An iron(II)-2-aminophenolate complex (see picture, right) with a tetradentate ligand reacts with dioxygen to cleave the aromatic C-C bond of 2-amino-4-tert-butylphenolate to form 4-tert-butyl-2-picolinate. This complex represents a functional model of 2-aminophenol-1,6-dioxygenase (APD) and 3-hydroxyanthranilate-3,4-dioxygenase (HAD).",

keywords = "biomimetic model, cleavage reactions, dioxygenases, enzyme models, iron",

author = "Biswarup Chakraborty and Paine, \{Tapan Kanti\}",

year = "2013",

month = jan,

day = "14",

doi = "10.1002/anie.201206922",

language = "English",

volume = "52",

pages = "920--924",

journal = "Angewandte Chemie - International Edition",

issn = "1433-7851",

publisher = "John Wiley and Sons Ltd",

number = "3",

}

TY - JOUR

T1 - Aromatic ring cleavage of 2-amino-4-tert-butylphenol by a nonheme iron(II) complex

T2 - Functional model of 2-aminophenol dioxygenases

AU - Chakraborty, Biswarup

AU - Paine, Tapan Kanti

PY - 2013/1/14

Y1 - 2013/1/14

N2 - Biomimetic aromatic ring cleavage: An iron(II)-2-aminophenolate complex (see picture, right) with a tetradentate ligand reacts with dioxygen to cleave the aromatic C-C bond of 2-amino-4-tert-butylphenolate to form 4-tert-butyl-2-picolinate. This complex represents a functional model of 2-aminophenol-1,6-dioxygenase (APD) and 3-hydroxyanthranilate-3,4-dioxygenase (HAD).

AB - Biomimetic aromatic ring cleavage: An iron(II)-2-aminophenolate complex (see picture, right) with a tetradentate ligand reacts with dioxygen to cleave the aromatic C-C bond of 2-amino-4-tert-butylphenolate to form 4-tert-butyl-2-picolinate. This complex represents a functional model of 2-aminophenol-1,6-dioxygenase (APD) and 3-hydroxyanthranilate-3,4-dioxygenase (HAD).

KW - biomimetic model

KW - cleavage reactions

KW - dioxygenases

KW - enzyme models

KW - iron

UR - https://www.scopus.com/pages/publications/84872282624

U2 - 10.1002/anie.201206922

DO - 10.1002/anie.201206922

M3 - Article

C2 - 23197337

AN - SCOPUS:84872282624

SN - 1433-7851

VL - 52

SP - 920

EP - 924

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 3

ER -

Aromatic ring cleavage of 2-amino-4-tert-butylphenol by a nonheme iron(II) complex: Functional model of 2-aminophenol dioxygenases

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this