Artificial intelligence in drug resistance management

Amir Elalouf, Hadas Elalouf, Ariel Rosenfeld, Hanan Maoz

Research output: Contribution to journalReview articlepeer-review

3 Scopus citations

Abstract

This review highlights the application of artificial intelligence (AI), particularly deep learning and machine learning (ML), in managing antimicrobial resistance (AMR). Key findings demonstrate that AI models, such as Naïve Bayes, Decision Trees (DT), Random Forest (RF), Support Vector Machines (SVM), and Artificial Neural Networks (ANN), have significantly advanced the prediction of drug resistance patterns and the identification of novel antibiotics. These algorithms have effectively optimized antibiotic use, predicted resistance phenotypes, and identified new drug candidates. AI has also facilitated the detection of AMR-associated mutations, offering new insights into the spread of resistance and potential interventions. Despite data privacy and algorithm transparency challenges, AI presents a promising tool in combating AMR, with implications for improving patient outcomes, enhancing disease management, and addressing global public health concerns. However, realizing its full potential requires overcoming issues related to data scarcity, ethical considerations, and fostering interdisciplinary collaboration.

Original languageEnglish
Article number126
Journal3 Biotech
Volume15
Issue number5
DOIs
StatePublished - 1 May 2025
Externally publishedYes

Keywords

  • AI applications
  • Antimicrobial resistance
  • Artificial intelligence
  • Drug resistance management

ASJC Scopus subject areas

  • Biotechnology
  • Environmental Science (miscellaneous)
  • Agricultural and Biological Sciences (miscellaneous)

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