Aspergillus wound infection in an immune-competent patient – A case report

Elchanan Quint, Ivan Kukeev, Hannah Glinter, Anton Osyntsov, Guy Barsky, Alex Vakhrushev, Evgeni Brotfain, Daniel Grupel

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Background: Abdominal aspergillosis is a life-threatening, opportunistic fungal infection that mainly affects immunocompromised patients. In this report, we present a case of abdominal surgical site aspergillosis in an immunocompetent patient. Case presentation: A 74-year-old immune-competent woman that had a prolonged hospitalization in the Intensive Care (ICU) Unit with several abdominal surgeries and multiple antibiotic treatment regimens. The abdomen remained open between interventions. 21 days following ICU admission a diagnosis of surgical site aspergillosis was made, treated with systemic and topical antifungal treatment. Conclusions: While nosocomial aspergillosis typically affects immunocompromised patients, immunocompetent patients also become susceptible when the skin barrier is broken and tissue is exposed to the environment. Treatment consisted with surgical debridement and systemic antifungal therapy. This case provides an example of extensive and rare surgical infection.

    Original languageEnglish
    Article number100146
    JournalClinical Infection in Practice
    Volume15
    DOIs
    StatePublished - 1 Jul 2022

    Keywords

    • Abdominal aspergillosis
    • Immune-competent
    • Open abdomen technique
    • Opportunistic infection

    ASJC Scopus subject areas

    • Infectious Diseases

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