Assessment of iodine nutrition status among school age children of Nepal by urinary iodine assay

B. Gelal, M. Aryal, B. K. Das Lal, B. Bhatta, M. Lamsal, N. Baral

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

The present study was undertaken to evaluate the iodine status of Nepalese school age children by measuring urinary iodine excretion (UIE). A population based cross-sectional study was conducted during November-December 2006 among 1,094 school age children. Spot urine samples were collected from all children and UIE was measured during February to March 2007 by an ammonium persulfate digestion microplate (APDM) method. The median UIE at the national level was 193.10 pg/1, indicating adequate iodine intake in Nepalese schoolchildren. The proportion of the population having UIE below 50 ug/1 and below 100 ug/1 were 4.5% and 22.0%, respectively. Determination of precision of the method was done following calculation of the inter- and intra-assay coefficient of variation (CV). At low, medium and high concentrations of urinary iodine the intra-assay CVs were 6.3, 1.8 and 1.9%, respectively. The inter-assay CVs for low, medium and high concentrations of urinary iodine were 11.9, 4.9 and 6.2%, respectively. Therefore, current iodine nutrition status is at satisfactory levels in Nepal. An effective monitoring program must be continued to ensure optimal iodine status and prevent the population from developing iodine deficiency disorder (IDD).

Original languageEnglish
Pages (from-to)538-543
Number of pages6
JournalSoutheast Asian Journal of Tropical Medicine and Public Health
Volume40
Issue number3
StatePublished - 1 Jan 2009
Externally publishedYes

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

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