Asymmetric homogeneous hydrogenation of α-acylaminocinnamic acids and esters catalyzed by a rhodium (I) complex of dioxop

D. Lafont, D. Sinou, G. Descotes, R. Glaser, S. Geresh

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

α-Acylaminocinnamic acids and esters are hydrogenated with rhodium (I) complex containing (2R, 4R)-cis-bis(diphenylphosphinomethyl)-1,3-dioxolan. The Z acids give enantiomeric excess up to 79% in the presence of triethylamine; increasing the steric bulk of the enamide moiety has only a small effect on the enantiomeric excess. The esters are reduced with low optical yield.

Original languageEnglish
Pages (from-to)305-311
Number of pages7
JournalJournal of Molecular Catalysis
Volume10
Issue number3
DOIs
StatePublished - 1 Jan 1981

Fingerprint

Dive into the research topics of 'Asymmetric homogeneous hydrogenation of α-acylaminocinnamic acids and esters catalyzed by a rhodium (I) complex of dioxop'. Together they form a unique fingerprint.

Cite this