TY - JOUR
T1 - Attention deficit hyperactivity disorder symptoms in patients with cystic fibrosis
AU - Cohen-Cymberknoh, Malena
AU - Tanny, Tzlil
AU - Breuer, Oded
AU - Blau, Hannah
AU - Mussaffi, Huda
AU - Kadosh, Diana
AU - Gartner, Silvia
AU - Salinas, Alma
AU - Bentur, Lea
AU - Nir, Vered
AU - Gur, Michal
AU - Reiter, Joel
AU - Shoseyov, David
AU - Kerem, Eitan
AU - Berger, Itai
N1 - Publisher Copyright:
© 2017 European Cystic Fibrosis Society
PY - 2018/3/1
Y1 - 2018/3/1
N2 - Background: Cystic fibrosis (CF) is a chronic life-threatening disease. In patients who suffer from chronic disease, Attention Deficit Hyperactivity Disorder (ADHD) is associated with functional impairment that can affect adherence to treatment and consequently influence prognosis. Methods: CF patients filled in the ADHD Rating Scale (ADHD-RS) adapted to the DSM5 and were assessed on a continuous performance task (MOXO-CPT), a standardized-computerized test designed to evaluate several domains of attention. Results: Of the 175 patients (99 males), 18% presented ADHD symptoms, according to ADHD-RS; 16% in the younger group (< 18 years), and 18.9% in the adult group. The male to female ratio was 3:1 in children and 1:1 in adults. Conclusions: The occurrence of ADHD symptoms in patients with CF is substantially higher than in the general population and should be recognized as a co-morbidity of CF. As ADHD can impair adherence to therapy, further research is needed to investigate the effect of ADHD therapy on adherence.
AB - Background: Cystic fibrosis (CF) is a chronic life-threatening disease. In patients who suffer from chronic disease, Attention Deficit Hyperactivity Disorder (ADHD) is associated with functional impairment that can affect adherence to treatment and consequently influence prognosis. Methods: CF patients filled in the ADHD Rating Scale (ADHD-RS) adapted to the DSM5 and were assessed on a continuous performance task (MOXO-CPT), a standardized-computerized test designed to evaluate several domains of attention. Results: Of the 175 patients (99 males), 18% presented ADHD symptoms, according to ADHD-RS; 16% in the younger group (< 18 years), and 18.9% in the adult group. The male to female ratio was 3:1 in children and 1:1 in adults. Conclusions: The occurrence of ADHD symptoms in patients with CF is substantially higher than in the general population and should be recognized as a co-morbidity of CF. As ADHD can impair adherence to therapy, further research is needed to investigate the effect of ADHD therapy on adherence.
KW - ADHD
KW - Adherence
KW - Chronic illness
KW - Cystic fibrosis
KW - Inflammatory disease
UR - http://www.scopus.com/inward/record.url?scp=85038844419&partnerID=8YFLogxK
U2 - 10.1016/j.jcf.2017.11.020
DO - 10.1016/j.jcf.2017.11.020
M3 - Article
AN - SCOPUS:85038844419
SN - 1569-1993
VL - 17
SP - 281
EP - 285
JO - Journal of Cystic Fibrosis
JF - Journal of Cystic Fibrosis
IS - 2
ER -
