Autoantibodies associated with atherosclerosis

Y. Shoenfeld, Y. Sherer, J. George, D. Harats

Research output: Contribution to journalArticlepeer-review

59 Scopus citations

Abstract

Atherosclerosis is a multifactorial pathological process. In recent years, the immune factors associated with its initiation and progression have been investigated intensively. Several autoantigens and their respective autoantibodies have been suggested as factors in atherogenesis. This manuscript provides a review of autoantibodies directed towards oxidized low-density lipoprotein (oxLDL), cardiolipin, β2-glycoprotein-I and heat-shock protein 60/65, and their association with human and murine atherosclerosis.

Original languageEnglish
Pages (from-to)37-40
Number of pages4
JournalAnnals of Medicine
Volume32
Issue numberSUPPL. 1
StatePublished - 1 Dec 2000
Externally publishedYes

Keywords

  • Antibody
  • Anticardiolipin
  • Atherosclerosis
  • Heat-shock protein
  • Oxidized low-density lipoprotein
  • β2-glycoprotein-I

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