B cell repertoire in patients with a novel BTK mutation: expanding the spectrum of atypical X-linked agammaglobulinemia

Keyphrases

• B Cell Repertoire 100%
• X-linked Agammaglobulinemia 100%
• BTK mutation 100%
• B Cells 60%
• BTK Gene 60%
• Heavy Chain 40%
• Next-generation Sequencing 40%
• Uneven Distribution 40%
• Circulating B Cells 40%
• Protein Expression 20%
• Clinical Records 20%
• Novel mutation 20%
• Nave 20%
• Clinical Data 20%
• Quantitative PCR 20%
• Next-generation Sequencing Technology 20%
• Immunoglobulin Heavy Chain 20%
• Hypomorphic mutation 20%
• Mild Phenotype 20%
• Bruton's Tyrosine Kinase 20%
• Atypical Case 20%
• Kappa-deleting Recombination Excision Circles 20%
• Repertoire Diversity 20%

Immunology and Microbiology

• B Cell 100%
• X-Linked Agammaglobulinemia 100%
• Next Generation Sequencing 42%
• Immunoglobulin Heavy Chain 42%
• Protein Expression 14%
• Real Time Polymerase Chain Reaction 14%
• Intron 14%
• Bruton Tyrosine Kinase 14%