Bacosides from Bacopa monnieri extract: An overview of the effects on neurological disorders

Samarpita Banerjee, Uttpal Anand, Suchhanda Ghosh, Durga Ray, Puja Ray, Samapika Nandy, Ganpat Dewaji Deshmukh, Vijay Tripathi, Abhijit Dey

Research output: Contribution to journalReview articlepeer-review

28 Scopus citations


From ancient history, complementary and alternative medicines have played a significant role as holistic therapeutic treatments of various human diseases including cancer, diabetes, neurological diseases, and skin problems. One Indian medicinal plant (herb), Bacopa monnieri has been used in many parts of the world as such medicine, particularly for the treatment of various neurological disorders. It is well known as a potent “tonic for the human brain,” which serves as a memory enhancer. Multiple studies proved that this herb contains a plethora of potential bioactive, phytochemical compounds with synergistic properties. The main purpose of the present review is to shed light on the use of Bacopa monnieri and its active principles (bacosides) in the management of neurological disorders. Furthermore, the signaling pathways modulated by bacosides have been critically discussed in this review. Moreover, we have critically summarized the present knowledge of this perennial creeping herb based upon the literature mining from different scientific engines.

Original languageEnglish
Pages (from-to)5668-5679
Number of pages12
JournalPhytotherapy Research
Issue number10
StatePublished - 1 Oct 2021


  • Bacopa monnieri
  • bioactive
  • complementary and alternative medicines
  • neurological disorders
  • nootropic
  • phytochemical

ASJC Scopus subject areas

  • Pharmacology


Dive into the research topics of 'Bacosides from Bacopa monnieri extract: An overview of the effects on neurological disorders'. Together they form a unique fingerprint.

Cite this