Bigger Isn’t Always Better: Data Considerations for Latent Class Analysis

  • Imogen S. Stafford
  • , Nophar Geifman

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Increasingly large datasets of clinical information present a significant opportunity to stratify patients for a more personalised approach to care. However, these data can be sparse and noisy, requiring processing of this data to be carefully considered. Here, we apply different minimum prevalence thresholds to diagnosis codes in a cohort of Multiple Sclerosis patients. We use this data to stratify patients using latent class analysis and examine the effect of different prevalence thresholds on the classes generated. We also examine computation efficiency using several disease-specific datasets.

Original languageEnglish
Title of host publicationIntelligent Health Systems - From Technology to Data and Knowledge, Proceedings of MIE 2025
EditorsElisavet Andrikopoulou, Parisis Gallos, Theodoros N. Arvanitis, Rosalynn Austin, Arriel Benis, Ronald Cornet, Panagiotis Chatzistergos, Alexander Dejaco, Linda Dusseljee-Peute, Alaa Mohasseb, Pantelis Natsiavas, Haythem Nakkas, Philip Scott
PublisherIOS Press BV
Pages447-451
Number of pages5
ISBN (Electronic)9781643685960
DOIs
StatePublished - 15 May 2025
Externally publishedYes
Event35th Medical Informatics Europe Conference, MIE 2025 - Glasgow, United Kingdom
Duration: 19 May 202521 May 2025

Publication series

NameStudies in Health Technology and Informatics
Volume327
ISSN (Print)0926-9630
ISSN (Electronic)1879-8365

Conference

Conference35th Medical Informatics Europe Conference, MIE 2025
Country/TerritoryUnited Kingdom
CityGlasgow
Period19/05/2521/05/25

Keywords

  • Big Data
  • ICD10
  • Latent Class Analysis
  • Multiple Sclerosis

ASJC Scopus subject areas

  • Biomedical Engineering
  • Health Informatics
  • Health Information Management

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