Bilateral Optogenetic Stimulation of the Olfactory Bulb of OMP-ChIEF Mice

Praveen Kuruppath

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Optogenetics has revolutionized the field of neuroscience by enabling the manipulation of specific neuronal populations with exceptional precision. Here, a robust method is described that integrates optogenetic stimulation of olfactory bulb glomeruli with foot shock fear conditioning. By merging the sophistication of optogenetics with the well-established principles of fear conditioning, this method opens new avenues for exploring the neural dynamics that drive adaptive behavioral responses to olfactory threats.

Original languageEnglish
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages189-200
Number of pages12
DOIs
StatePublished - 1 Jan 2025
Externally publishedYes

Publication series

NameMethods in Molecular Biology
Volume2915
ISSN (Print)1064-3745
ISSN (Electronic)1940-6029

Keywords

  • Channelrhodopsin-2
  • Foot shock
  • Light zone
  • Olfactory bulb
  • Optogenetics
  • Safe zone

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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