Abstract
The biology of the fibroblast growth factor (FGF) gene family is reviewed. The structure, expression and known and putative functions of the seven members of this family characterized to date are discussed. These genes include: acidic and basic FGF, the INT.2 and HST proto-oncogenes and the recently characterized FGF.5, FGF.6 and KGF genes. These genes play a role in various processes such as cell proliferation, angiogenesis and embryogenesis, and possibly carcinogenesis.
| Original language | English |
|---|---|
| Pages (from-to) | 212-219 |
| Number of pages | 8 |
| Journal | Israel Journal of Medical Sciences |
| Volume | 26 |
| Issue number | 4 |
| State | Published - 1 Jan 1990 |
Keywords
- amplification
- angiogenesis
- growth factors
- mesoderm induction
- oncogenes
- transformation
ASJC Scopus subject areas
- Bioengineering