Biology of the fibroblast growth factor gene family

D. Benharroch, D. Birnbaum

    Research output: Contribution to journalReview articlepeer-review

    41 Scopus citations


    The biology of the fibroblast growth factor (FGF) gene family is reviewed. The structure, expression and known and putative functions of the seven members of this family characterized to date are discussed. These genes include: acidic and basic FGF, the INT.2 and HST proto-oncogenes and the recently characterized FGF.5, FGF.6 and KGF genes. These genes play a role in various processes such as cell proliferation, angiogenesis and embryogenesis, and possibly carcinogenesis.

    Original languageEnglish
    Pages (from-to)212-219
    Number of pages8
    JournalIsrael Journal of Medical Sciences
    Issue number4
    StatePublished - 1 Jan 1990


    • amplification
    • angiogenesis
    • growth factors
    • mesoderm induction
    • oncogenes
    • transformation

    ASJC Scopus subject areas

    • Bioengineering


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