Biopsy-free Virtual Histology of Skin Using Reflectance Confocal Microscopy and Deep Learning

Jingxi Li; Jason Garfinkel; Xiaoran Zhang; Di Wu; Yijie Zhang; Kevin de Haan; Hongda Wang; Tairan Liu; Bijie Bai; Yair Rivenson; Gennady Rubinstein; Philip O. Scumpia; Aydogan Ozcan

Biopsy-free Virtual Histology of Skin Using Reflectance Confocal Microscopy and Deep Learning

Jingxi Li
, Jason Garfinkel
, Xiaoran Zhang
, Di Wu
, Yijie Zhang
, Kevin de Haan
, Hongda Wang
, Tairan Liu
, Bijie Bai
, Yair Rivenson
, Gennady Rubinstein
, Philip O. Scumpia
, Aydogan Ozcan

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

We report in vivo virtual histology of skin without a biopsy, where deep learning is used to virtually stain tissue and generate hematoxylin and eosin (H&E)-like microscopic images of skin using a reflectance confocal microscope.

Original language	English
Title of host publication	2022 Conference on Lasers and Electro-Optics, CLEO 2022 - Proceedings
Publisher	Institute of Electrical and Electronics Engineers
ISBN (Electronic)	9781957171050
State	Published - 1 Jan 2022
Externally published	Yes
Event	2022 Conference on Lasers and Electro-Optics, CLEO 2022 - San Jose, United States Duration: 15 May 2022 → 20 May 2022

Publication series

Name	2022 Conference on Lasers and Electro-Optics, CLEO 2022 - Proceedings

Conference

Conference	2022 Conference on Lasers and Electro-Optics, CLEO 2022
Country/Territory	United States
City	San Jose
Period	15/05/22 → 20/05/22

ASJC Scopus subject areas

Instrumentation
Spectroscopy
Biomedical Engineering
Electrical and Electronic Engineering
Management, Monitoring, Policy and Law
Materials Science (miscellaneous)
Acoustics and Ultrasonics
Atomic and Molecular Physics, and Optics

Cite this

Li, J., Garfinkel, J., Zhang, X., Wu, D., Zhang, Y., de Haan, K., Wang, H., Liu, T., Bai, B., Rivenson, Y., Rubinstein, G., Scumpia, P. O., & Ozcan, A. (2022). Biopsy-free Virtual Histology of Skin Using Reflectance Confocal Microscopy and Deep Learning. In 2022 Conference on Lasers and Electro-Optics, CLEO 2022 - Proceedings Article ATh2I.3 (2022 Conference on Lasers and Electro-Optics, CLEO 2022 - Proceedings). Institute of Electrical and Electronics Engineers.

@inproceedings{810a13773c364743b0743a4a84d171e5,

title = "Biopsy-free Virtual Histology of Skin Using Reflectance Confocal Microscopy and Deep Learning",

abstract = "We report in vivo virtual histology of skin without a biopsy, where deep learning is used to virtually stain tissue and generate hematoxylin and eosin (H\&E)-like microscopic images of skin using a reflectance confocal microscope.",

author = "Jingxi Li and Jason Garfinkel and Xiaoran Zhang and Di Wu and Yijie Zhang and \{de Haan\}, Kevin and Hongda Wang and Tairan Liu and Bijie Bai and Yair Rivenson and Gennady Rubinstein and Scumpia, \{Philip O.\} and Aydogan Ozcan",

note = "Publisher Copyright: {\textcopyright} Optica Publishing Group 2022, {\textcopyright} 2022 The Author(s); 2022 Conference on Lasers and Electro-Optics, CLEO 2022 ; Conference date: 15-05-2022 Through 20-05-2022",

year = "2022",

month = jan,

day = "1",

language = "English",

series = "2022 Conference on Lasers and Electro-Optics, CLEO 2022 - Proceedings",

publisher = "Institute of Electrical and Electronics Engineers",

booktitle = "2022 Conference on Lasers and Electro-Optics, CLEO 2022 - Proceedings",

address = "United States",

}

Li, J, Garfinkel, J, Zhang, X, Wu, D, Zhang, Y, de Haan, K, Wang, H, Liu, T, Bai, B, Rivenson, Y, Rubinstein, G, Scumpia, PO & Ozcan, A 2022, Biopsy-free Virtual Histology of Skin Using Reflectance Confocal Microscopy and Deep Learning. in 2022 Conference on Lasers and Electro-Optics, CLEO 2022 - Proceedings., ATh2I.3, 2022 Conference on Lasers and Electro-Optics, CLEO 2022 - Proceedings, Institute of Electrical and Electronics Engineers, 2022 Conference on Lasers and Electro-Optics, CLEO 2022, San Jose, United States, 15/05/22.

Biopsy-free Virtual Histology of Skin Using Reflectance Confocal Microscopy and Deep Learning. / Li, Jingxi; Garfinkel, Jason; Zhang, Xiaoran et al.
2022 Conference on Lasers and Electro-Optics, CLEO 2022 - Proceedings. Institute of Electrical and Electronics Engineers, 2022. ATh2I.3 (2022 Conference on Lasers and Electro-Optics, CLEO 2022 - Proceedings).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Biopsy-free Virtual Histology of Skin Using Reflectance Confocal Microscopy and Deep Learning

AU - Li, Jingxi

AU - Garfinkel, Jason

AU - Zhang, Xiaoran

AU - Wu, Di

AU - Zhang, Yijie

AU - de Haan, Kevin

AU - Wang, Hongda

AU - Liu, Tairan

AU - Bai, Bijie

AU - Rivenson, Yair

AU - Rubinstein, Gennady

AU - Scumpia, Philip O.

AU - Ozcan, Aydogan

PY - 2022/1/1

Y1 - 2022/1/1

N2 - We report in vivo virtual histology of skin without a biopsy, where deep learning is used to virtually stain tissue and generate hematoxylin and eosin (H&E)-like microscopic images of skin using a reflectance confocal microscope.

AB - We report in vivo virtual histology of skin without a biopsy, where deep learning is used to virtually stain tissue and generate hematoxylin and eosin (H&E)-like microscopic images of skin using a reflectance confocal microscope.

UR - https://www.scopus.com/pages/publications/85139959390

M3 - Conference contribution

AN - SCOPUS:85139959390

T3 - 2022 Conference on Lasers and Electro-Optics, CLEO 2022 - Proceedings

BT - 2022 Conference on Lasers and Electro-Optics, CLEO 2022 - Proceedings

PB - Institute of Electrical and Electronics Engineers

T2 - 2022 Conference on Lasers and Electro-Optics, CLEO 2022

Y2 - 15 May 2022 through 20 May 2022

ER -

Biopsy-free Virtual Histology of Skin Using Reflectance Confocal Microscopy and Deep Learning

Abstract

Publication series

Conference

ASJC Scopus subject areas

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