Biopsy-free Virtual Histology of Skin Using Reflectance Confocal Microscopy and Deep Learning

Jingxi Li; Jason Garfinkel; Xiaoran Zhang; Di Wu; Yijie Zhang; Kevin de Haan; Hongda Wang; Tairan Liu; Bijie Bai; Yair Rivenson; Gennady Rubinstein; Philip O. Scumpia; Aydogan Ozcan

Biopsy-free Virtual Histology of Skin Using Reflectance Confocal Microscopy and Deep Learning

Jingxi Li
, Jason Garfinkel
, Xiaoran Zhang
, Di Wu
, Yijie Zhang
, Kevin de Haan
, Hongda Wang
, Tairan Liu
, Bijie Bai
, Yair Rivenson
, Gennady Rubinstein
, Philip O. Scumpia
, Aydogan Ozcan

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

We report in vivo virtual histology of skin without a biopsy, where deep learning is used to virtually stain tissue and generate hematoxylin and eosin (H&E)-like microscopic images of skin using a reflectance confocal microscope.

Original language	English
Title of host publication	CLEO
Subtitle of host publication	Applications and Technology, A and T 2022
Publisher	Optica Publishing Group (formerly OSA)
ISBN (Electronic)	9781957171050
State	Published - 1 Jan 2022
Externally published	Yes
Event	CLEO: Applications and Technology, A and T 2022 - San Jose, United States Duration: 15 May 2022 → 20 May 2022

Publication series

Name	Optics InfoBase Conference Papers
ISSN (Electronic)	2162-2701

Conference

Conference	CLEO: Applications and Technology, A and T 2022
Country/Territory	United States
City	San Jose
Period	15/05/22 → 20/05/22

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Mechanics of Materials

Cite this

Li, J., Garfinkel, J., Zhang, X., Wu, D., Zhang, Y., de Haan, K., Wang, H., Liu, T., Bai, B., Rivenson, Y., Rubinstein, G., Scumpia, P. O., & Ozcan, A. (2022). Biopsy-free Virtual Histology of Skin Using Reflectance Confocal Microscopy and Deep Learning. In CLEO: Applications and Technology, A and T 2022 Article ATh2I.3 (Optics InfoBase Conference Papers). Optica Publishing Group (formerly OSA).

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title = "Biopsy-free Virtual Histology of Skin Using Reflectance Confocal Microscopy and Deep Learning",

abstract = "We report in vivo virtual histology of skin without a biopsy, where deep learning is used to virtually stain tissue and generate hematoxylin and eosin (H\&E)-like microscopic images of skin using a reflectance confocal microscope.",

author = "Jingxi Li and Jason Garfinkel and Xiaoran Zhang and Di Wu and Yijie Zhang and \{de Haan\}, Kevin and Hongda Wang and Tairan Liu and Bijie Bai and Yair Rivenson and Gennady Rubinstein and Scumpia, \{Philip O.\} and Aydogan Ozcan",

note = "Publisher Copyright: {\textcopyright} Optica Publishing Group 2022, {\textcopyright} 2022 The Author(s); CLEO: Applications and Technology, A and T 2022 ; Conference date: 15-05-2022 Through 20-05-2022",

year = "2022",

month = jan,

day = "1",

language = "English",

series = "Optics InfoBase Conference Papers",

publisher = "Optica Publishing Group (formerly OSA)",

booktitle = "CLEO",

}

Li, J, Garfinkel, J, Zhang, X, Wu, D, Zhang, Y, de Haan, K, Wang, H, Liu, T, Bai, B, Rivenson, Y, Rubinstein, G, Scumpia, PO & Ozcan, A 2022, Biopsy-free Virtual Histology of Skin Using Reflectance Confocal Microscopy and Deep Learning. in CLEO: Applications and Technology, A and T 2022., ATh2I.3, Optics InfoBase Conference Papers, Optica Publishing Group (formerly OSA), CLEO: Applications and Technology, A and T 2022, San Jose, United States, 15/05/22.

Biopsy-free Virtual Histology of Skin Using Reflectance Confocal Microscopy and Deep Learning. / Li, Jingxi; Garfinkel, Jason; Zhang, Xiaoran et al.
CLEO: Applications and Technology, A and T 2022. Optica Publishing Group (formerly OSA), 2022. ATh2I.3 (Optics InfoBase Conference Papers).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Biopsy-free Virtual Histology of Skin Using Reflectance Confocal Microscopy and Deep Learning

AU - Li, Jingxi

AU - Garfinkel, Jason

AU - Zhang, Xiaoran

AU - Wu, Di

AU - Zhang, Yijie

AU - de Haan, Kevin

AU - Wang, Hongda

AU - Liu, Tairan

AU - Bai, Bijie

AU - Rivenson, Yair

AU - Rubinstein, Gennady

AU - Scumpia, Philip O.

AU - Ozcan, Aydogan

PY - 2022/1/1

Y1 - 2022/1/1

N2 - We report in vivo virtual histology of skin without a biopsy, where deep learning is used to virtually stain tissue and generate hematoxylin and eosin (H&E)-like microscopic images of skin using a reflectance confocal microscope.

AB - We report in vivo virtual histology of skin without a biopsy, where deep learning is used to virtually stain tissue and generate hematoxylin and eosin (H&E)-like microscopic images of skin using a reflectance confocal microscope.

UR - https://www.scopus.com/pages/publications/85136818740

M3 - Conference contribution

AN - SCOPUS:85136818740

T3 - Optics InfoBase Conference Papers

BT - CLEO

PB - Optica Publishing Group (formerly OSA)

T2 - CLEO: Applications and Technology, A and T 2022

Y2 - 15 May 2022 through 20 May 2022

ER -

Biopsy-free Virtual Histology of Skin Using Reflectance Confocal Microscopy and Deep Learning

Abstract

Publication series

Conference

ASJC Scopus subject areas

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Cite this