Bioreceptor functionalization of gold-coated sensor surfaces

Daria Prilutsky, Lev Tsapovsky, Robert S. Marks

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


Another popular and powerful surface modification strategy is self-assembly: it is easy to apply, which makes it possible to change or tune the surface character by modifying the end groups of the layer accurately and predictably. The self-assembly strategy, which forms surfaces with stimuli-responsive properties, is also known as smart surfaces and is discussed in the following section. 3.3.1  Thiol-Gold Coordination: Self-Assembled 

Monolayers (SAMs)The process of self-assembly involves the spontaneous non-covalent arrangements of atoms and molecules to form a functional unity toward an energetically stable form, whose novel structure and properties are determined by their nature.24 Natural and prominent examples of self-assembly are provided by double-helical25 and triple-helical DNA,26 multichromophore structures of the photosynthetic reaction center,27 and light-harvesting antennae apparatus.28 Among self-assembly strategies, the generation of a self-assembled monolayer (SAM) is one of the most elegant ways to create a film with specific surface properties.4A self-assembled monolayer is a layer of molecular thickness formed by self-organization of active surfactant molecules in an ordered manner on a solid surface
Original languageEnglish
Title of host publicationNanoantenna
Subtitle of host publicationPlasmon Enhanced Spectroscopies for Biotechnological Applications
PublisherPan Stanford Publishing Pte. Ltd.
Number of pages51
ISBN (Print)9789814303613
StatePublished - 30 Sep 2012

ASJC Scopus subject areas

  • General Physics and Astronomy
  • General Engineering
  • General Biochemistry, Genetics and Molecular Biology


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