Biosensor and method of detection of a DNA sequence

Serge A Cosnier (Inventor), Robert S Marks (Inventor), Elena R Ionescu (Inventor)

Research output: Patent

Abstract

The invention relates biosensor comprising a conductive or
semi-conductive Support and an intercalator polymer, wherein the intercalator polymer comprises monomer units of formula (I) wherein P is an electropolymerizable moiety selected among the group consisting in pyrrole, acetylene, phenol, aniline, thiophene, carbazole and azulene; Sp is a spacer, and Im is an intercalator.
The invention also relates to a method for the detection of a
DNA sequence with the biosensor, comprising the steps of hybridizing the DNA sequence with a DNA probe for forming a dsDNA incubating the biosensor with the dsDNA for anchoring the dsDNA to the intercalator detecting the quantity of dsDNA on the biosensor.
Original languageEnglish GB
Patent numberUS 7,947,836 B2
StatePublished - 1 May 2011

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