Biosensors based on combined optical and electrochemical transduction for molecular diagnostics

Evgeni Eltzov, Serge Cosnier, Robert S. Marks

Research output: Contribution to journalReview articlepeer-review

31 Scopus citations

Abstract

Electrochemical and optical biosensors exist to monitor different fluids containing analytes of interest. Until today, these have been developed separately. Owing to the creation of new transducer configurations such as indium tin-coated glass fiber optics, these methods can now be used separately, in parallel and it is hoped that one day they will be able to be used simultaneously; thus, using the same probe to measure a single analyte using two different methods (electrochemical and optical) or two different analytes with either of the aforementioned methods sitting on the same probe. This article will highlight the importance, as well as the usefulness, of combining measurement methodologies in improving sensor response and sensitivity.

Original languageEnglish
Pages (from-to)533-546
Number of pages14
JournalExpert Review of Molecular Diagnostics
Volume11
Issue number5
DOIs
StatePublished - 1 Jun 2011

Keywords

  • biosensor
  • dual platform
  • electrochemistry
  • enzyme
  • optical fiber

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Molecular Medicine
  • Molecular Biology
  • Genetics

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