Biosynthesis of silver nanoparticles using latex from few euphorbian plants and their antimicrobial potential

Satish V. Patil, Hemant P. Borase, Chandrashekhar D. Patil, Bipinchandra K. Salunke

Research output: Contribution to journalArticlepeer-review

113 Scopus citations


The synthesis of well-dispersed and ultrafine metal nanoparticles has great interest due to their distinctive physicochemical properties and biomedical applications. This study is the first report of one-step solvent-free synthesis of AgNPs using Euphorbiaceae plant latex. Among evaluated eight latex-producing plants, four (Jatropha curcas, Jatropha gossypifolia, Pedilanthus tithymaloides, and Euphorbia milii) showed high potential to produce physicochemically distinct, small-sized and bactericidal AgNPs. Phytochemical screening showed presence of rich amount of biochemicals in these plants. J. gossypifolia showed uniformly dispersed comparatively small-sized AgNPs. Dose-dependent growth inhibition of bacterial pathogens Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Staphylococcus epidermis, and Micrococcus luteus was observed for J. gossypifolia latex-synthesized AgNPs with minimum inhibitory concentration values 30, 40, 70, 60, and 60 ppm, respectively, after 24 h. Possible mode of action of AgNPs against pathogens was confirmed by analyzing enzymes and cell leakage.

Original languageEnglish
Pages (from-to)776-790
Number of pages15
JournalApplied Biochemistry and Biotechnology
Issue number4
StatePublished - 1 Jun 2012
Externally publishedYes


  • Antimicrobial
  • Euphorbiaceae
  • Jatropha gossypifolia
  • Latex
  • Nanoparticles
  • Zeta potential

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology


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