Biotechnological advancement in an important medicinal plant, Withania coagulans: An overview and recent updates

Mangal S. Rathore, Kusum Khatri, Jasminkumar Kheni, Narpat S. Shekhawat

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

2 Scopus citations


Withania coagulans (Stocks) Dunal is an important and high-value medicinal plant of Solanaceae. It is popularly called Indian cheese maker or vegetable rennet. Plant possesses multiple medicinal properties, and the reproductive failure and overexploitation from wild habitat forced this species towards the verge of complete extinction. Plant tissue culture and recent advancements in the field of biotechnology like genomics, proteomics and metabolomics have enormous potential for the genetic improvement of plant species and facilitate the development of new methods for plant germplasm conservation, evaluation and improvement. Though W. coagulans is known for multiple medicinal properties, however, it has not been given considerable attention for genetic improvement. The present chapter will focus on the development and recent contribution of advanced biotechnological interventions in genetic improvement of W. coagulans. This chapter will provide a comprehensive information on the development of in vitro methods for conservation of germplasm, mass-scale multiplication and their employment in genetic transformation and secondary metabolite production. Further genomics, proteomics and metabolomics updates on W. coagulans have been discussed, and these will facilitate researchers a ready-to-use source of information.

Original languageEnglish
Title of host publicationBiotechnological Approaches for Medicinal and Aromatic Plants
Subtitle of host publicationConservation, Genetic Improvement and Utilization
PublisherSpringer Singapore
Number of pages21
ISBN (Electronic)9789811305351
ISBN (Print)9789811305344
StatePublished - 1 Jan 2018
Externally publishedYes


  • Ashwagandha
  • Encapsulation
  • Genomics and metabolomics
  • Germplasm conservation
  • In vitro clonal propagation
  • Withanolides

ASJC Scopus subject areas

  • General Agricultural and Biological Sciences
  • General Biochemistry, Genetics and Molecular Biology
  • General Environmental Science


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