The aim of the study was to investigate the influence of escitalopram on peripheral body temperature (PBT) in panic disorder. In a 4 week case-control study (N = 12 female patients; N = 12 matched healthy controls), the daytime PBT declined compared to night time PBT in patients. The prospective relationship between PBT and panic disorder shows a decline of daytime PBT compared to the night time PBT in panic disorder from week 2 of treatment with escitalopram onwards. The effect of escitalopram on daytime PBT may have occurred through an activation of the sympathetic system.
- Body temperature
- Panic disorder