@article{e08e18b2626e47c1b52a8797be1f8283,
title = "Brain Network Analysis of EEG Recordings Can Be Used to Assess Cognitive Function in Teenagers With 15q13.3 Microdeletion Syndrome",
abstract = "15q13.3 microdeletion syndrome causes a spectrum of cognitive disorders, including intellectual disability and autism. We assessed the ability of the EEG analysis algorithm Brain Network Analysis (BNA) to measure cognitive function in 15q13.3 deletion patients, and to differentiate between patient and control groups. EEG data was collected from 10 individuals with 15q13.3 microdeletion syndrome (14–18 years of age), as well as 30 age-matched healthy controls, as the subjects responded to Auditory Oddball (AOB) and Go/NoGo cognitive tasks. It was determined that BNA can be used to evaluate cognitive function in 15q13.3 microdeletion patients. This analysis also significantly differentiates between patient and control groups using 5 scores, all of which are produced from ERP peaks related to late cortical components that represent higher cognitive functions of attention allocation and response inhibition (P < 0.05).",
keywords = "15q13.3, CHRNA7, EEG, ERP, Go/No-Go, auditory oddball, brain network analytics, microdeletion",
author = "Tehila Stern and Crutcher, {Emeline H.} and McCarthy, {John M.} and Ali, {May A.} and Gil Issachar and Amir Geva and Ziv Peremen and Schaaf, {Christian P.}",
note = "Funding Information: This work was supported by the Office of the Assistant Secretary of Defense for Health Affairs, through the Autism Research Program under Award No. W81XWH-17-1-0369. Opinions, interpretations, conclusions, and recommendations are those of the author and are not necessarily endorsed by the Department of Defense. Funding Information: We thank Dr. Revital Shani-Hershkovich and Dr. Offir Laufer who provided insights and expertise that assisted the research and helped to improve the manuscript. Funding. This work was supported by the Office of the Assistant Secretary of Defense for Health Affairs, through the Autism Research Program under Award No. W81XWH-17-1-0369. Opinions, interpretations, conclusions, and recommendations are those of the author and are not necessarily endorsed by the Department of Defense. Publisher Copyright: {\textcopyright} Copyright {\textcopyright} 2021 Stern, Crutcher, McCarthy, Ali, Issachar, Geva, Peremen and Schaaf.",
year = "2021",
month = jan,
day = "28",
doi = "10.3389/fnins.2021.622329",
language = "English",
volume = "15",
journal = "Frontiers in Neuroscience",
issn = "1662-4548",
publisher = "Frontiers Media S.A.",
}