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Brain sarcoma of meningeal origin after cranial irradiation in childhood acute lymphocytic leukemia

  • P. Tiberin
  • , E. Maor
  • , R. Zaizov
  • , I. J. Cohen
  • , M. Hirsch
  • , T. Yosefovich
  • , J. Ronen
  • , J. Goldstein

Research output: Contribution to journalArticlepeer-review

41 Scopus citations

Abstract

The authors report their experience with an unusual case of intracerebral sarcoma of meningeal cell origin in an 8 1/2 -year-old girl. This tumor occurred 6 1/2 years after cranial irradiation at relatively low dosage (2200 rads) had been delivered to the head in the course of a mutlimodality treatment for acute lymphocytic leukemia. The tumor recurred approximately 10 months after the first surgical intervention. Macroscopic total excision of the recurrent growth followed by whole-brain irradiation (4500 rads) failed to eradicate it completely and local recurrence prompted reoperation 18 months later. This complication of treatment in long-term childhood leukemia survivors is briefly discussed, as well as the pathology of meningeal sarcomas.

Original languageEnglish
Pages (from-to)772-776
Number of pages5
JournalJournal of Neurosurgery
Volume61
Issue number4
DOIs
StatePublished - 1 Jan 1984

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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