Break on through to the other side - The Sec translocon

Jerry Eichler, Franck Duong

Research output: Contribution to journalShort surveypeer-review

9 Scopus citations

Abstract

The transfer of newly synthesized polypeptides across the membrane occurs at the translocon. Although the central role of the translocon in protein translocation is understood, much regarding the manner by which these membrane protein complexes function remains to be learned. The recent solution of the crystal structure of a Sec complex, together with other biochemical, biophysical and structural findings, suggests that answers might be forthcoming.

Original languageEnglish
Pages (from-to)221-223
Number of pages3
JournalTrends in Biochemical Sciences
Volume29
Issue number5
DOIs
StatePublished - 1 May 2004

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