Bromocriptine in hyperprolactinemic amenorrhea: A possible early effect on ovarian steroidogenesis

D. Le Roith, G. Potashnik, S. Glick

    Research output: Contribution to journalArticlepeer-review

    1 Scopus citations

    Abstract

    The effect of bromocriptine was studied in a 28-year-old cretin woman who presented with long-term untreated primary hypothyroidism, primary amenorrhea, hyperprolactinemia, and an enlarged pituitary fossa. Bromocriptine therapy lowered the plasma prolactin and caused an early rise in plasma 17β-estradiol levels and uterine bleeding, despite the failure of plasma gonadotrophins to respond to luteinizing hormone release hormone (LHRH) administration. Thus, it is suggested that bromocriptine may have an early direct effect on the ovary in hyperprolactinemic amenorrhea.

    Original languageEnglish
    Pages (from-to)145-147
    Number of pages3
    JournalInternational Journal of Fertility
    Volume24
    Issue number2
    StatePublished - 1 Dec 1979

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