Bubble dynamics in double-stranded DNA

Grégoire Altan-Bonnet; Albert Libchaber; Oleg Krichevsky

Bubble dynamics in double-stranded DNA

Grégoire Altan-Bonnet, Albert Libchaber, Oleg Krichevsky

Department of Physics

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

The fluctuation dynamics of DNA breathing modes was measured. It was found that bubbles of 2 to 10 base pairs with lifetimes in the 50 μs range spontaneously open in dsDNA at 37deg;C, under low salt condition (0.1 M). The existence of these long-lived fluctuating bubbles adds a new and interesting dimension to the dynamical picture of DNA behavior and of DNA-protein interactions.

Original language	English
Article number	138101
Pages (from-to)	138101/1-138101/4
Journal	Physical Review Letters
Volume	90
Issue number	13
State	Published - 4 Apr 2003

ASJC Scopus subject areas

General Physics and Astronomy

Cite this

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title = "Bubble dynamics in double-stranded DNA",

abstract = "The fluctuation dynamics of DNA breathing modes was measured. It was found that bubbles of 2 to 10 base pairs with lifetimes in the 50 μs range spontaneously open in dsDNA at 37deg;C, under low salt condition (0.1 M). The existence of these long-lived fluctuating bubbles adds a new and interesting dimension to the dynamical picture of DNA behavior and of DNA-protein interactions.",

author = "Gr{\'e}goire Altan-Bonnet and Albert Libchaber and Oleg Krichevsky",

year = "2003",

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language = "English",

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T1 - Bubble dynamics in double-stranded DNA

AU - Altan-Bonnet, Grégoire

AU - Libchaber, Albert

AU - Krichevsky, Oleg

PY - 2003/4/4

Y1 - 2003/4/4

N2 - The fluctuation dynamics of DNA breathing modes was measured. It was found that bubbles of 2 to 10 base pairs with lifetimes in the 50 μs range spontaneously open in dsDNA at 37deg;C, under low salt condition (0.1 M). The existence of these long-lived fluctuating bubbles adds a new and interesting dimension to the dynamical picture of DNA behavior and of DNA-protein interactions.

AB - The fluctuation dynamics of DNA breathing modes was measured. It was found that bubbles of 2 to 10 base pairs with lifetimes in the 50 μs range spontaneously open in dsDNA at 37deg;C, under low salt condition (0.1 M). The existence of these long-lived fluctuating bubbles adds a new and interesting dimension to the dynamical picture of DNA behavior and of DNA-protein interactions.

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M3 - Article

AN - SCOPUS:33744959916

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JO - Physical Review Letters

JF - Physical Review Letters

IS - 13

M1 - 138101

ER -

Bubble dynamics in double-stranded DNA

Abstract

ASJC Scopus subject areas

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