Bulk Modification of Carbon Paste Electrode with Bi2O3 Nanoparticles and Its Application as an Electrochemical Sensor for Selective Sensing of Anti-HIV Drug Nevirapine

Nagappa L. Teradal; J. Seetharamappa

doi:10.1002/elan.201500088

Bulk Modification of Carbon Paste Electrode with Bi₂O₃ Nanoparticles and Its Application as an Electrochemical Sensor for Selective Sensing of Anti-HIV Drug Nevirapine

Nagappa L. Teradal, J. Seetharamappa

Research output: Contribution to journal › Article › peer-review

39 Scopus citations

Abstract

Bi₂O₃ nanoparticles were synthesized by solution combustion method and utilized for fabrication of an electrochemical sensor [carbon paste electrode modified with Bi₂O₃ (CPE-Bi₂O₃)] for nevirapine (NVP). Electrode materials were characterized by XRD, FTIR, TG-DTA, AFM and SEM-EDS methods. CPE-Bi₂O₃ was electroreduced (Er) in KOH in the potential range of -1.3-0V to obtain CPE-ErBi₂O₃. CPE-ErBi₂O₃ exhibited electrocatalytic activity towards the oxidation of NVP. Under optimized conditions, linearity between the peak current and NVP concentration was observed in the range of 0.05-50μM. Further, the sensor was used for the assay of NVP in tablets and biological samples.

Original language	English
Pages (from-to)	2007-2016
Number of pages	10
Journal	Electroanalysis
Volume	27
Issue number	8
DOIs	https://doi.org/10.1002/elan.201500088
State	Published - 1 Aug 2015
Externally published	Yes

Keywords

Analytical applications
CPE-ErBiO
Electrocatalytic activity
Nevirapine

ASJC Scopus subject areas

Analytical Chemistry
Electrochemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1002/elan.201500088

Cite this

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title = "Bulk Modification of Carbon Paste Electrode with Bi2O3 Nanoparticles and Its Application as an Electrochemical Sensor for Selective Sensing of Anti-HIV Drug Nevirapine",

abstract = "Bi2O3 nanoparticles were synthesized by solution combustion method and utilized for fabrication of an electrochemical sensor [carbon paste electrode modified with Bi2O3 (CPE-Bi2O3)] for nevirapine (NVP). Electrode materials were characterized by XRD, FTIR, TG-DTA, AFM and SEM-EDS methods. CPE-Bi2O3 was electroreduced (Er) in KOH in the potential range of -1.3-0V to obtain CPE-ErBi2O3. CPE-ErBi2O3 exhibited electrocatalytic activity towards the oxidation of NVP. Under optimized conditions, linearity between the peak current and NVP concentration was observed in the range of 0.05-50μM. Further, the sensor was used for the assay of NVP in tablets and biological samples.",

keywords = "Analytical applications, CPE-ErBiO, Electrocatalytic activity, Nevirapine",

author = "Teradal, {Nagappa L.} and J. Seetharamappa",

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AU - Seetharamappa, J.

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N2 - Bi2O3 nanoparticles were synthesized by solution combustion method and utilized for fabrication of an electrochemical sensor [carbon paste electrode modified with Bi2O3 (CPE-Bi2O3)] for nevirapine (NVP). Electrode materials were characterized by XRD, FTIR, TG-DTA, AFM and SEM-EDS methods. CPE-Bi2O3 was electroreduced (Er) in KOH in the potential range of -1.3-0V to obtain CPE-ErBi2O3. CPE-ErBi2O3 exhibited electrocatalytic activity towards the oxidation of NVP. Under optimized conditions, linearity between the peak current and NVP concentration was observed in the range of 0.05-50μM. Further, the sensor was used for the assay of NVP in tablets and biological samples.

AB - Bi2O3 nanoparticles were synthesized by solution combustion method and utilized for fabrication of an electrochemical sensor [carbon paste electrode modified with Bi2O3 (CPE-Bi2O3)] for nevirapine (NVP). Electrode materials were characterized by XRD, FTIR, TG-DTA, AFM and SEM-EDS methods. CPE-Bi2O3 was electroreduced (Er) in KOH in the potential range of -1.3-0V to obtain CPE-ErBi2O3. CPE-ErBi2O3 exhibited electrocatalytic activity towards the oxidation of NVP. Under optimized conditions, linearity between the peak current and NVP concentration was observed in the range of 0.05-50μM. Further, the sensor was used for the assay of NVP in tablets and biological samples.

KW - Analytical applications

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