C-reactive protein as a predictor for chorioamnionitis in cases of premature rupture of the membranes

Y. Romem, R. Artal

Research output: Contribution to journalArticlepeer-review

71 Scopus citations

Abstract

We evaluated C-reactive protein for its ability to predict the occurrence of clinical chorioamnionitis in 51 patients with spontaneous premature rupture of the membranes at ≤ 34 weeks of gestational age. All the patients had determinations of C-reactive protein on admission, and then 25 patients were tested daily. Of the total 51 patients, 14 developed clinical signs compatible with a diagnosis of chorioamnionitis. An analysis was conducted to compare the use of C-reactive protein to that of white blood cell count in predicting febrile disease. Our study indicates that C-reactive protein is an accurate and early marker for predicting clinical chorioamnionitis. White blood cell and differential counts are less accurate in such prediction, especially after steroid treatment.

Original languageEnglish
Pages (from-to)546-550
Number of pages5
JournalAmerican Journal of Obstetrics and Gynecology
Volume150
Issue number5
DOIs
StatePublished - 1 Jan 1984
Externally publishedYes

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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