Abstract
The caged cell-penetrating peptide (cCPP) conjugates of this invention are ideal for intracellular delivery of a broad variety of cargoes including various nanoparticle pharmaceutical carriers (liposomes, micelles, microparticles, nanoparticles, polymer-conjugates). The conjugates comprise a detectable agent or a therapeutic agent, and the conjugates provide a novel strategy for site-specific delivery of the same to appropriate tissues in the subject. Versatile application of the conjugates in diagnostics and imaging is described.
| Original language | English |
|---|---|
| Patent number | US2019225653 |
| IPC | A61K 49/ 00 A I |
| Priority date | 30/11/18 |
| State | Published - 25 Jul 2019 |