Cannabielsoic acids. Isolation and synthesis by a novel oxidative cyclization

A. Shani, R. Mechoulam

Research output: Contribution to journalArticlepeer-review

60 Scopus citations


Two tricyclic dihydrobenzofuran cannabinoids, cannabielsoic acids A (4a) and B (5a) were isolated from hashish. Their structures were elucidated by chemical transformations and from spectral data. Cannabielsoic acid A was synthesized from cannabidiolic acid by an oxidative cyclization in the presence of air under irradiation, or with manganese dioxide.

Original languageEnglish
Pages (from-to)2437-2446
Number of pages10
Issue number15
StatePublished - 1 Jan 1974

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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