TY - JOUR
T1 - Carbon Dot-Decorated Polystyrene Microspheres for Whispering-Gallery Mode Biosensing
AU - Starovoytov, Anton A.
AU - Soloveva, Evgeniia O.
AU - Kurassova, Kamilla
AU - Bogdanov, Kirill V.
AU - Arefina, Irina A.
AU - Shevchenko, Natalia N.
AU - Vartanyan, Tigran A.
AU - Dadadzhanov, Daler R.
AU - Toropov, Nikita A.
N1 - Publisher Copyright:
© 2024 by the authors.
PY - 2024/5/1
Y1 - 2024/5/1
N2 - Whispering gallery mode (WGM) resonators doped with fluorescent materials find impressive applications in biological sensing. They do not require special conditions for the excitation of WGM inside that provide the basis for in vivo sensing. Currently, the problem of materials for in vivo WGM sensors are substantial since their fluorescence should have stable optical properties as well as they should be biocompatible. To address this we present WGM microresonators of 5–7 (Formula presented.) m, where the dopant is made of carbon quantum dots (CDs). CDs are biocompatible since they are produced from carbon and demonstrate bright optical emission, which shows different bands depending on the excitation wavelength. The WGM sensors developed here were tested as label-free biosensors by detecting bovine serum albumin molecules. The results showed WGM frequency shifting, with the limit of detection down to (Formula presented.) M level.
AB - Whispering gallery mode (WGM) resonators doped with fluorescent materials find impressive applications in biological sensing. They do not require special conditions for the excitation of WGM inside that provide the basis for in vivo sensing. Currently, the problem of materials for in vivo WGM sensors are substantial since their fluorescence should have stable optical properties as well as they should be biocompatible. To address this we present WGM microresonators of 5–7 (Formula presented.) m, where the dopant is made of carbon quantum dots (CDs). CDs are biocompatible since they are produced from carbon and demonstrate bright optical emission, which shows different bands depending on the excitation wavelength. The WGM sensors developed here were tested as label-free biosensors by detecting bovine serum albumin molecules. The results showed WGM frequency shifting, with the limit of detection down to (Formula presented.) M level.
KW - biosensing
KW - bovine serum albumin
KW - carbon dots
KW - microsphere
KW - whispering gallery modes
UR - http://www.scopus.com/inward/record.url?scp=85194171339&partnerID=8YFLogxK
U2 - 10.3390/photonics11050480
DO - 10.3390/photonics11050480
M3 - Article
AN - SCOPUS:85194171339
SN - 2304-6732
VL - 11
JO - Photonics
JF - Photonics
IS - 5
M1 - 480
ER -