Case report: Serendipitous Gaucher's disease presenting as elevated erythrocyte sedimentation rate due to monoclonal gammopathy

Y. Liel, M. J. Hausmann, M. Mozes

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13 Scopus citations

Abstract

Immunoglobulin abnormalities have not been previously noted in totally asymptomatic patients with Gaucher's disease. We report a 40-year-old woman in whom Gaucher's disease was diagnosed during investigation for incidentally discovered elevated erythrocyte sedimentation rate. Further studies revealed IgG(λ) monoclonal gammopathy. Physical examination and a bone survey disclosed none of the features of Gaucher's disease or multiple myeloma. We conclude that in contrast with previous observations, paraproteinemia may occur with Gaucher's disease even in the absence of splenomegaly or any one of the other features of the disease.

Original languageEnglish
Pages (from-to)393-394
Number of pages2
JournalAmerican Journal of the Medical Sciences
Volume301
Issue number6
DOIs
StatePublished - 1 Jan 1991
Externally publishedYes

Keywords

  • Clinical presentation
  • Gaucher's disease
  • Lymphocyte subtypes
  • Monoclonal gammopathy

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