Catalysis of Organic Reactions through Halogen Bonding

Revannath L. Sutar, Stefan M. Huber

Research output: Contribution to journalReview articlepeer-review

149 Scopus citations

Abstract

Halogen bonding, the noncovalent interaction based on electrophilic halogen substituents, features very interesting properties, as illustrated by numerous applications continuously emerging in recent years, and is by now sometimes considered as a hydrophobic and soft analogue of the well-known hydrogen bond. Conventionally studied both in silico and in the solid state, its solution-phase applications particularly for catalyzing organic transformations are currently under active investigation. Herein we present a conceptual treatise on the latest developments in this regard and discuss the challenges associated with the advancement of more practical catalytic halogen-bonding systems.

Original languageEnglish
Pages (from-to)9622-9639
Number of pages18
JournalACS Catalysis
Volume9
Issue number10
DOIs
StatePublished - 4 Oct 2019
Externally publishedYes

Keywords

  • halogen bonding
  • halogens
  • noncovalent interactions
  • organocatalysis
  • σ-hole

ASJC Scopus subject areas

  • Catalysis
  • Chemistry (all)

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