Catalytic Antibodies in Natural Products Synthesis

Ashraf Brik, Ehud Keinan

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Scopus citations
Original languageEnglish
Title of host publicationCatalytic Antibodies
PublisherWiley-VCH Verlag
Number of pages21
ISBN (Electronic)9783527603664
ISBN (Print)3527306889, 9783527306886
StatePublished - 13 May 2005
Externally publishedYes


  • Antibody-catalyzed asymmetric protonolysis of an enol ether
  • Catalytic antibodies
  • Formation of steroid A and B rings via cationic cyclization
  • In natural products synthesis
  • Resolution of tertiary aldols with 38C2
  • Synthesis of (+)-frontalin and mevalonolactone
  • Synthesis of 1-deoxy-L-xylose
  • Synthesis of naproxen via antibody-catalyzed ester hydrolysis
  • Total synthesis of a-multistriatin
  • Total synthesis of brevicomins using aldolase antibody 38C2
  • Total synthesis of epothilones
  • Wieland-Miescher ketone via 38C2-catalyzed Robinson annulation

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology (all)

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