Cation requirement of natural, in-vitro generated and antibody dependent killing exerted by human lymphocytes

S. Argov; A. Poros; E. Klein

doi:10.1016/s0340-904x(79)80058-5

Cation requirement of natural, in-vitro generated and antibody dependent killing exerted by human lymphocytes

S. Argov, A. Poros, E. Klein

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Three cytotoxic systems, NK, ADCC and the seemingly indiscriminative cytotoxicity of in vitro activated lymphocytes (cultivated with K 562) were found to require Ca⁺⁺ and did not function in Mg⁺⁺. The optimum concentration of Ca⁺⁺ was identical for the three systems and for various lymphocyte subsets. 15 minutes after initiation of the interaction cell damage had already occurred in all three systems.

Original language	English
Pages (from-to)	25-34
Number of pages	10
Journal	Immunobiology
Volume	156
Issue number	1-2
DOIs	https://doi.org/10.1016/s0340-904x(79)80058-5
State	Published - 1 Jan 1979
Externally published	Yes

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Hematology

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10.1016/s0340-904x(79)80058-5

Cite this

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title = "Cation requirement of natural, in-vitro generated and antibody dependent killing exerted by human lymphocytes",

abstract = "Three cytotoxic systems, NK, ADCC and the seemingly indiscriminative cytotoxicity of in vitro activated lymphocytes (cultivated with K 562) were found to require Ca++ and did not function in Mg++. The optimum concentration of Ca++ was identical for the three systems and for various lymphocyte subsets. 15 minutes after initiation of the interaction cell damage had already occurred in all three systems.",

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AU - Poros, A.

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N2 - Three cytotoxic systems, NK, ADCC and the seemingly indiscriminative cytotoxicity of in vitro activated lymphocytes (cultivated with K 562) were found to require Ca++ and did not function in Mg++. The optimum concentration of Ca++ was identical for the three systems and for various lymphocyte subsets. 15 minutes after initiation of the interaction cell damage had already occurred in all three systems.

AB - Three cytotoxic systems, NK, ADCC and the seemingly indiscriminative cytotoxicity of in vitro activated lymphocytes (cultivated with K 562) were found to require Ca++ and did not function in Mg++. The optimum concentration of Ca++ was identical for the three systems and for various lymphocyte subsets. 15 minutes after initiation of the interaction cell damage had already occurred in all three systems.

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AN - SCOPUS:0018606351

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ER -

Cation requirement of natural, in-vitro generated and antibody dependent killing exerted by human lymphocytes

Abstract

ASJC Scopus subject areas

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