Cation requirement of natural, in-vitro generated and antibody dependent killing exerted by human lymphocytes

S. Argov; A. Poros; E. Klein

doi:10.1016/s0340-904x(79)80058-5

Cation requirement of natural, in-vitro generated and antibody dependent killing exerted by human lymphocytes

S. Argov, A. Poros, E. Klein

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Three cytotoxic systems, NK, ADCC and the seemingly indiscriminative cytotoxicity of in vitro activated lymphocytes (cultivated with K 562) were found to require Ca⁺⁺ and did not function in Mg⁺⁺. The optimum concentration of Ca⁺⁺ was identical for the three systems and for various lymphocyte subsets. 15 minutes after initiation of the interaction cell damage had already occurred in all three systems.

Original language	English
Pages (from-to)	25-34
Number of pages	10
Journal	Immunobiology
Volume	156
Issue number	1-2
DOIs	https://doi.org/10.1016/s0340-904x(79)80058-5
State	Published - 1 Jan 1979
Externally published	Yes

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Hematology

Access to Document

10.1016/s0340-904x(79)80058-5

Cite this

@article{cdb2c5a31c6042478aca402d6b751c70,

title = "Cation requirement of natural, in-vitro generated and antibody dependent killing exerted by human lymphocytes",

abstract = "Three cytotoxic systems, NK, ADCC and the seemingly indiscriminative cytotoxicity of in vitro activated lymphocytes (cultivated with K 562) were found to require Ca++ and did not function in Mg++. The optimum concentration of Ca++ was identical for the three systems and for various lymphocyte subsets. 15 minutes after initiation of the interaction cell damage had already occurred in all three systems.",

author = "S. Argov and A. Poros and E. Klein",

year = "1979",

month = jan,

day = "1",

doi = "10.1016/s0340-904x(79)80058-5",

language = "English",

volume = "156",

pages = "25--34",

journal = "Immunobiology",

issn = "0171-2985",

publisher = "Elsevier GmbH",

number = "1-2",

}

TY - JOUR

T1 - Cation requirement of natural, in-vitro generated and antibody dependent killing exerted by human lymphocytes

AU - Argov, S.

AU - Poros, A.

AU - Klein, E.

PY - 1979/1/1

Y1 - 1979/1/1

N2 - Three cytotoxic systems, NK, ADCC and the seemingly indiscriminative cytotoxicity of in vitro activated lymphocytes (cultivated with K 562) were found to require Ca++ and did not function in Mg++. The optimum concentration of Ca++ was identical for the three systems and for various lymphocyte subsets. 15 minutes after initiation of the interaction cell damage had already occurred in all three systems.

AB - Three cytotoxic systems, NK, ADCC and the seemingly indiscriminative cytotoxicity of in vitro activated lymphocytes (cultivated with K 562) were found to require Ca++ and did not function in Mg++. The optimum concentration of Ca++ was identical for the three systems and for various lymphocyte subsets. 15 minutes after initiation of the interaction cell damage had already occurred in all three systems.

UR - https://www.scopus.com/pages/publications/0018606351

U2 - 10.1016/s0340-904x(79)80058-5

DO - 10.1016/s0340-904x(79)80058-5

M3 - Article

C2 - 540969

AN - SCOPUS:0018606351

SN - 0171-2985

VL - 156

SP - 25

EP - 34

JO - Immunobiology

JF - Immunobiology

IS - 1-2

ER -

Cation requirement of natural, in-vitro generated and antibody dependent killing exerted by human lymphocytes

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this