Cefuroxime-induced encephalopathy

Y. O. Herishanu; M. Zlotnik; M. Mostoslavsky; M. Podgaietski; S. Frisher; I. Wirguin

doi:10.1212/WNL.50.6.1873

Cefuroxime-induced encephalopathy

Y. O. Herishanu, M. Zlotnik, M. Mostoslavsky, M. Podgaietski, S. Frisher, I. Wirguin

Research output: Contribution to journal › Article › peer-review

36 Scopus citations

Abstract

We describe four patients who developed an encephalopathic syndrome characterized by obtundation or stupor, myoclonic jerks, and asterixis in association with cefuroxime therapy. Three patients had renal failure. These cases suggest that cefuroxime in overdose or in conventional doses in patients with renal failure can cause a reversible encephalopathy. This syndrome may have been unrecognized because it usually occurs in severely ill patients with additional causes for encephalopathy.

Original language	English
Pages (from-to)	1873-1875
Number of pages	3
Journal	Neurology
Volume	50
Issue number	6
DOIs	https://doi.org/10.1212/WNL.50.6.1873
State	Published - 1 Jan 1998

ASJC Scopus subject areas

Clinical Neurology

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AU - Herishanu, Y. O.

AU - Zlotnik, M.

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AU - Frisher, S.

AU - Wirguin, I.

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N2 - We describe four patients who developed an encephalopathic syndrome characterized by obtundation or stupor, myoclonic jerks, and asterixis in association with cefuroxime therapy. Three patients had renal failure. These cases suggest that cefuroxime in overdose or in conventional doses in patients with renal failure can cause a reversible encephalopathy. This syndrome may have been unrecognized because it usually occurs in severely ill patients with additional causes for encephalopathy.

AB - We describe four patients who developed an encephalopathic syndrome characterized by obtundation or stupor, myoclonic jerks, and asterixis in association with cefuroxime therapy. Three patients had renal failure. These cases suggest that cefuroxime in overdose or in conventional doses in patients with renal failure can cause a reversible encephalopathy. This syndrome may have been unrecognized because it usually occurs in severely ill patients with additional causes for encephalopathy.

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Cefuroxime-induced encephalopathy

Abstract

ASJC Scopus subject areas

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